Microbiology & Immunology

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Microbiology & Immunology focuses on the study of microorganisms and the immune system, explaining how microbes interact with living organisms and how the body defends itself against infections. This category is designed for Class 11–12 students, NEET aspirants, and undergraduate learners to build strong conceptual and applied understanding.

In this section, you will study:

  • Classification and characteristics of microorganisms

  • Structure and life cycles of bacteria, viruses, fungi, and protozoa

  • Beneficial and harmful roles of microorganisms

  • Principles of innate and acquired immunity

  • Cells and organs of the immune system

  • Antigens, antibodies, and immune responses

  • Vaccination and immunological memory

  • Basics of immune disorders and hypersensitivity

  • NCERT-based explanations, diagrams, MCQs, and exam-oriented questions

The content is structured to develop conceptual clarity, enhance diagram and mechanism-based understanding, and help students perform confidently in school examinations, NEET, and undergraduate assessments.

Build a strong foundation in microbiology and immunology to understand disease, immunity, and the biological basis of health and protection.

Q. In a case study, a hospital outbreak was traced back to improperly sterilized endoscopes. What is the best practice to prevent such outbreaks?
  • A. Use single-use instruments
  • B. Increase the frequency of cleaning
  • C. Implement strict sterilization protocols
  • D. Use chemical disinfectants only
Q. In a case study, a surgical instrument was found to be contaminated with Staphylococcus aureus. Which sterilization method would be most effective?
  • A. Boiling water
  • B. Ethylene oxide gas
  • C. Alcohol wipes
  • D. Ultraviolet light
Q. In a clinical trial, a vaccine shows a 70% efficacy rate. If 1,000 individuals are vaccinated, how many are expected to be protected?
  • A. 700
  • B. 300
  • C. 500
  • D. 900
Q. In a laboratory diagnosis of tuberculosis, which test is most commonly used to assess cell-mediated immunity?
  • A. ELISA
  • B. Mantoux test
  • C. Blood culture
  • D. PCR
Q. In a laboratory setting, which method is most appropriate for sterilizing heat-sensitive liquids?
  • A. Autoclaving
  • B. Filtration
  • C. Incineration
  • D. Chemical sterilization
Q. In a study, 200 patients were infected with a virus. If 40% of them developed symptoms, how many patients showed symptoms?
  • A. 80
  • B. 60
  • C. 40
  • D. 20
Q. In which scenario would you use a high-level disinfectant?
  • A. For cleaning floors
  • B. For sterilizing surgical instruments
  • C. For disinfecting semi-critical items like endoscopes
  • D. For routine hand hygiene
Q. What is herd immunity?
  • A. Immunity developed by individuals after infection
  • B. Immunity that protects a population when a large percentage is vaccinated
  • C. Immunity that occurs naturally in a population
  • D. Immunity that is passed from mother to child
Q. What is the appropriate concentration of hydrogen peroxide for high-level disinfection?
  • A. 3%
  • B. 6%
  • C. 30%
  • D. 50%
Q. What is the D-value for a microorganism if it takes 5 minutes to reduce the population by 90% at 121°C?
  • A. 1 minute
  • B. 2 minutes
  • C. 5 minutes
  • D. 10 minutes
Q. What is the function of memory B cells?
  • A. To produce antibodies immediately
  • B. To remember past infections
  • C. To activate T cells
  • D. To phagocytize pathogens
Q. What is the function of memory cells in the immune system?
  • A. To produce immediate immune responses
  • B. To remember past infections and respond quickly upon re-exposure
  • C. To activate macrophages
  • D. To secrete cytokines
Q. What is the function of memory T cells?
  • A. Immediate response to pathogens
  • B. Long-term immunity
  • C. Production of antibodies
  • D. Activation of macrophages
Q. What is the function of the complement system in immunity?
  • A. To produce antibodies
  • B. To lyse pathogens
  • C. To activate T cells
  • D. To enhance inflammation
Q. What is the half-life of IgG antibodies in the human body?
  • A. 1-2 days
  • B. 5-7 days
  • C. 21 days
  • D. 23 days
Q. What is the main advantage of using steam sterilization over dry heat sterilization?
  • A. Faster sterilization time
  • B. Lower temperatures required
  • C. More effective against spores
  • D. All of the above
Q. What is the main difference between disinfection and sterilization?
  • A. Disinfection kills all microbes; sterilization does not
  • B. Sterilization kills all microbes; disinfection reduces microbial load
  • C. Disinfection is used on inanimate objects; sterilization is not
  • D. There is no difference
Q. What is the main difference between sterilization and disinfection?
  • A. Sterilization kills all microbes; disinfection reduces them
  • B. Disinfection kills all microbes; sterilization reduces them
  • C. Sterilization is faster than disinfection
  • D. Disinfection is only for surfaces, sterilization is for instruments
Q. What is the main function of cytotoxic T cells?
  • A. Produce antibodies
  • B. Kill infected or cancerous cells
  • C. Activate B cells
  • D. Secrete cytokines
Q. What is the main function of phagocytes in the immune system?
  • A. To produce antibodies
  • B. To present antigens
  • C. To engulf and digest pathogens
  • D. To secrete cytokines
Q. What is the main mode of transmission for the influenza virus?
  • A. Vector-borne
  • B. Airborne
  • C. Direct contact
  • D. Fecal-oral
Q. What is the main purpose of a booster vaccine?
  • A. To initiate the immune response
  • B. To enhance the immune memory
  • C. To provide immediate protection
  • D. To replace the primary vaccine
Q. What is the main purpose of the complement system in immunity?
  • A. To produce antibodies
  • B. To enhance inflammation and opsonization
  • C. To directly kill pathogens
  • D. To activate T cells
Q. What is the main purpose of the complement system?
  • A. To produce antibodies
  • B. To enhance phagocytosis and lyse pathogens
  • C. To activate T cells
  • D. To produce cytokines
Q. What is the main purpose of the Gram stain in microbiology?
  • A. To identify viral infections
  • B. To differentiate bacterial species
  • C. To determine antibiotic susceptibility
  • D. To visualize fungal structures
Q. What is the mechanism of action of the vaccine for measles, mumps, and rubella (MMR)?
  • A. Live attenuated virus
  • B. Inactivated virus
  • C. Subunit vaccine
  • D. Toxoid vaccine
Q. What is the minimum effective concentration of alcohol for disinfection?
  • A. 50%
  • B. 70%
  • C. 90%
  • D. 100%
Q. What is the minimum effective concentration of bleach for disinfection?
  • A. 0.5%
  • B. 1%
  • C. 5%
  • D. 10%
Q. What is the minimum effective concentration of ethanol for disinfection?
  • A. 50%
  • B. 70%
  • C. 90%
  • D. 100%
Q. What is the minimum effective temperature for autoclaving to ensure sterilization?
  • A. 100°C
  • B. 121°C
  • C. 130°C
  • D. 150°C
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