Central Dogma: Transcription & Translation

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The Central Dogma explains the flow of genetic information from DNA to RNA to protein. This category focuses on the mechanisms of transcription and translation, which are fundamental to gene expression and cellular function. It is suitable for Class 11–12 students, NEET aspirants, and undergraduate learners.

In this section, you will study:

  • Concept of the central dogma of molecular biology

  • Structure and types of RNA

  • Transcription process in prokaryotes and eukaryotes

  • Genetic code and its properties

  • Translation process and role of ribosomes, tRNA, and mRNA

  • Post-transcriptional and post-translational modifications

  • Regulation of gene expression at transcriptional and translational levels

  • NCERT-based explanations, diagrams, MCQs, and exam-oriented questions

The content is structured to build strong conceptual understanding, improve process-based and sequence-oriented reasoning, and help students perform confidently in school examinations, NEET, and undergraduate assessments.

Develop a clear understanding of how genetic information is expressed as functional proteins through transcription and translation.

Q. During transcription, which enzyme is responsible for synthesizing RNA from a DNA template?
  • A. DNA polymerase
  • B. RNA polymerase
  • C. Ribosome
  • D. Ligase
Q. In eukaryotic cells, where does transcription occur?
  • A. Cytoplasm
  • B. Nucleus
  • C. Mitochondria
  • D. Ribosome
Q. What is a codon?
  • A. A sequence of three nucleotides in DNA
  • B. A sequence of three nucleotides in RNA
  • C. A type of amino acid
  • D. A protein structure
Q. What is the function of ribosomes in the process of translation?
  • A. To synthesize DNA
  • B. To provide a site for protein synthesis
  • C. To transport RNA
  • D. To degrade proteins
Q. What is the primary function of mRNA in the central dogma of molecular biology?
  • A. To replicate DNA
  • B. To carry genetic information from DNA to ribosomes
  • C. To synthesize proteins
  • D. To form the structure of ribosomes
Q. What is the role of tRNA during translation?
  • A. To carry amino acids to the ribosome
  • B. To synthesize mRNA
  • C. To unwind DNA
  • D. To form peptide bonds
Q. What is the significance of the promoter region in a gene?
  • A. It codes for the protein
  • B. It is where RNA polymerase binds to initiate transcription
  • C. It terminates transcription
  • D. It is a coding sequence
Q. Which mutation results in a change in a single amino acid in a protein?
  • A. Silent mutation
  • B. Nonsense mutation
  • C. Missense mutation
  • D. Frameshift mutation
Q. Which of the following best describes the process of translation?
  • A. DNA is copied into RNA
  • B. RNA is converted into a protein
  • C. Proteins are degraded
  • D. RNA is replicated
Q. Which of the following processes occurs first in the central dogma?
  • A. Translation
  • B. Replication
  • C. Transcription
  • D. Protein folding
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