Central Dogma: Transcription & Translation - Higher Difficulty Problems

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This section is dedicated to challenging and conceptually demanding problems based on transcription and translation. It is designed for advanced Class 11–12 students, NEET aspirants targeting top ranks, and undergraduate learners who want to rigorously test and strengthen their conceptual depth and exam readiness.

In this section, you will work on:

  • Multi-concept problems integrating transcription, RNA processing, and translation

  • High-level MCQs requiring close NCERT line interpretation

  • Assertion–reason and multi-statement questions

  • Complex scenarios involving mutations affecting gene expression

  • Analytical problems on genetic code, wobble hypothesis, and translation accuracy

  • Diagram- and pathway-based reasoning questions

  • Previous-year inspired and high-trap competitive questions

The content is structured to enhance analytical thinking, improve accuracy under pressure, and prepare students to handle the toughest questions in NEET and other competitive examinations.

Sharpen your reasoning skills and master complexity by practicing higher-difficulty problems in transcription and translation.

Q. In the context of the central dogma, what does 'translation' refer to?
  • A. The process of copying DNA into RNA
  • B. The synthesis of proteins from mRNA
  • C. The replication of DNA
  • D. The modification of RNA
Q. What is the function of tRNA during translation?
  • A. To carry amino acids to the ribosome
  • B. To synthesize mRNA
  • C. To form the ribosome structure
  • D. To splice introns from mRNA
Q. What is the primary function of RNA polymerase during transcription?
  • A. To synthesize DNA from RNA
  • B. To synthesize RNA from a DNA template
  • C. To degrade RNA molecules
  • D. To replicate DNA
Q. What is the role of the promoter in gene expression?
  • A. To terminate transcription
  • B. To enhance translation
  • C. To initiate transcription
  • D. To splice RNA
Q. What is the significance of the 5' cap and poly-A tail in mRNA?
  • A. They are involved in DNA replication
  • B. They protect mRNA from degradation and assist in translation
  • C. They are required for transcription initiation
  • D. They help in the splicing of introns
Q. Which of the following is NOT a component of the RNA structure?
  • A. Ribose sugar
  • B. Phosphate group
  • C. Deoxyribose sugar
  • D. Nitrogenous bases
Q. Which of the following processes directly follows transcription?
  • A. Replication
  • B. Translation
  • C. Splicing
  • D. Translocation
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