Q. During which phase of mitosis do the chromosomes align at the cell's equatorial plane?
-
A.
Prophase
-
B.
Metaphase
-
C.
Anaphase
-
D.
Telophase
Solution
In metaphase, chromosomes line up at the metaphase plate before being separated.
Correct Answer:
B
— Metaphase
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Q. What is the main event that occurs during anaphase?
-
A.
Chromosomes condense
-
B.
Sister chromatids separate
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C.
Nuclear envelope reforms
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D.
Chromosomes align
Solution
During anaphase, sister chromatids are pulled apart to opposite poles of the cell.
Correct Answer:
B
— Sister chromatids separate
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Q. What is the primary purpose of the G1 checkpoint in the cell cycle?
-
A.
To check DNA integrity
-
B.
To ensure proper chromosome alignment
-
C.
To assess cell size and nutrients
-
D.
To initiate cytokinesis
Solution
The G1 checkpoint assesses cell size, nutrients, and DNA integrity before proceeding to DNA synthesis.
Correct Answer:
C
— To assess cell size and nutrients
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Q. What is the role of the spindle fibers during mitosis?
-
A.
To replicate DNA
-
B.
To separate sister chromatids
-
C.
To condense chromosomes
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D.
To reform the nuclear envelope
Solution
Spindle fibers attach to kinetochores and help separate sister chromatids during mitosis.
Correct Answer:
B
— To separate sister chromatids
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Q. What phase of the cell cycle is characterized by DNA replication?
-
A.
G1 phase
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B.
S phase
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C.
G2 phase
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D.
M phase
Solution
The S phase is where DNA replication occurs, resulting in the duplication of chromosomes.
Correct Answer:
B
— S phase
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Q. What triggers the onset of apoptosis during the cell cycle?
-
A.
DNA damage
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B.
Cell size
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C.
Nutrient availability
-
D.
Spindle assembly checkpoint
Solution
Severe DNA damage can trigger apoptosis to prevent the propagation of damaged cells.
Correct Answer:
A
— DNA damage
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Q. Which of the following is NOT a phase of mitosis?
-
A.
Prophase
-
B.
Metaphase
-
C.
Interphase
-
D.
Telophase
Solution
Interphase is not a phase of mitosis; it is the phase where the cell prepares for division.
Correct Answer:
C
— Interphase
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Q. Which phase of the cell cycle is known as the resting phase?
-
A.
G0 phase
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B.
G1 phase
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C.
S phase
-
D.
M phase
Solution
The G0 phase is a resting state where cells are not actively preparing to divide.
Correct Answer:
A
— G0 phase
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Q. Which protein complex is crucial for the transition from G2 phase to mitosis?
-
A.
Cyclin D
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B.
Cyclin A
-
C.
Cyclin B
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D.
Cyclin E
Solution
Cyclin B forms a complex with CDK1, which is essential for the G2 to M phase transition.
Correct Answer:
C
— Cyclin B
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